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Medical Pharmacology, Medical Faculty of the Safarik University, Kosice,Slovakia Contact Ján Moj¥iš, Associate Professor of Pharmacology,Department of Pharmacology of the
Medical Faculty of the Safarik University Tr. SNP 1, 040 66 Košice, Slovak Republic. Tel. 00421-95- 6423534. Fax. 00421-95-6428524.
E-mail. mojzis@central.medic.upjs.sk Teaching Curriculum
Introduction and general principles. Historical backgrownd.
Pharmacokinetic basis of drug action. Passage of drugs across membranes. Drug absorption.
October
Distribution of drugs. Plasma protein binding. Volume of distribution.
Elimination of drugs. Biotransformation and excretion of drugs.
How drugs act: molecular aspects, drug receptor interactions, second messengers.
Effects of age and disease on drug disposition. Genetic aspects of drug action.
Unwanted drug effects, allergy, drug abuse.
November
Chemical transmission and the autonomic nervous system. Cholinergic transmission. Ganglionic blocking agents, myorelaxants.
Drugs affecting adrenergic nervous system.
Chemical transmission and drug action in the central nervous system. Antipsychotic drugs.
Antidepressants, antianxiety, psychostimulants and psychodysleptics.
December
Drugs used in treating motor disorders: epilepsy, Parkinsonism, hypnotics. .
General and local anaesthetics.
Analgesic drugs. Opioid analgesic drugs.
Nicotine, alcohols, cannabis
February
The drugs used in treating respiratory disorders
Treatment of gastric ulcer. Laxatives. Antidiarrhoeals.
Antianginal drugs and drugs used in treating dysrhytmias
Heart failure and cardiac glycosides
March
Antihypertensive drugs
Drugs affecting hemostasis. Antianemic drugs
Corticosteroids, estrogenes and androgenes - therapeutic uses
Antidiabetic drugs and drugs used in treating of lipid metabolism disorder
Basic principles of chemotherapy. Penicillins and cephalosporins
April
Broad spectrum antibiotics. Antibiotics used in dentistry
The drugs used in chemotherapy of neoplastic disease
Antivomiting drugs. Histamine and antihistaminics
May
Drug poisoning and antidotal therapy
The drugs used in dentistry
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